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Resource "Sequence" Version "1" (StructureDefinition)

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XML or JSON representation. Try out the Profile as a questionnaire based web form . Edit this as XML or JSON. provenance for this resource

NameFlagsCard.TypeDescription & Constraintsdoco
.. Sequence ΣIDomainResourceInformation about a biological sequence
+ Only 0 and 1 are valid for coordinateSystem
Elements defined in Ancestors: id, meta, implicitRules, language, text, contained, extension, modifierExtension
... identifier Σ0..*IdentifierUnique ID for this particular sequence. This is a FHIR-defined id
... type Σ0..1codeaa | dna | rna
sequenceType (Example)
... coordinateSystem Σ1..1integerBase number of coordinate system (0 for 0-based numbering or coordinates, inclusive start, exclusive end, 1 for 1-based numbering, inclusive start, inclusive end)
... patient Σ0..1Reference(Patient)Who and/or what this is about
... specimen Σ0..1Reference(Specimen)Specimen used for sequencing
... device Σ0..1Reference(Device)The method for sequencing
... performer Σ0..1Reference(Organization)Who should be responsible for test result
... quantity Σ0..1QuantityThe number of copies of the seqeunce of interest. (RNASeq)
... referenceSeq ΣI0..1BackboneElementA sequence used as reference
+ Only +1 and -1 are valid for strand
+ GenomeBuild and chromosome must be both contained if either one of them is contained
+ Have and only have one of the following elements in referenceSeq : 1. genomeBuild ; 2 referenceSeqId; 3. referenceSeqPointer; 4. referenceSeqString;
.... chromosome Σ0..1CodeableConceptChromosome containing genetic finding
chromosome-human (Example)
.... genomeBuild Σ0..1stringThe Genome Build used for reference, following GRCh build versions e.g. 'GRCh 37'
.... referenceSeqId Σ0..1CodeableConceptReference identifier
ENSEMBL (Example)
.... referenceSeqPointer Σ0..1Reference(Sequence)A Pointer to another Sequence entity as reference sequence
.... referenceSeqString Σ0..1stringA string to represent reference sequence
.... strand Σ0..1integerDirectionality of DNA ( +1/-1)
.... windowStart Σ1..1integerStart position of the window on the reference sequence
.... windowEnd Σ1..1integerEnd position of the window on the reference sequence
... variant Σ0..*BackboneElementVariant in sequence
.... start Σ0..1integerStart position of the variant on the reference sequence
.... end Σ0..1integerEnd position of the variant on the reference sequence
.... observedAllele Σ0..1stringAllele that was observed
.... referenceAllele Σ0..1stringAllele in the reference sequence
.... cigar Σ0..1stringExtended CIGAR string for aligning the sequence with reference bases
.... variantPointer Σ0..1Reference(Observation)Pointer to observed variant information
... observedSeq Σ0..1stringSequence that was observed
... quality Σ0..*BackboneElementAn set of value as quality of sequence
.... type Σ1..1codeindel | snp | unknown
qualityType (Required)
.... standardSequence Σ0..1CodeableConceptStandard sequence for comparison
FDA-StandardSequence (Example)
.... start Σ0..1integerStart position of the sequence
.... end Σ0..1integerEnd position of the sequence
.... score Σ0..1QuantityQuality score for the comparison
.... method Σ0..1CodeableConceptMethod to get quality
FDA-Method (Example)
.... truthTP Σ0..1decimalTrue positives from the perspective of the truth data
.... queryTP Σ0..1decimalTrue positives from the perspective of the query data
.... truthFN Σ0..1decimalFalse negatives
.... queryFP Σ0..1decimalFalse positives
.... gtFP Σ0..1decimalFalse positives where the non-REF alleles in the Truth and Query Call Sets match
.... precision Σ0..1decimalPrecision of comparison
.... recall Σ0..1decimalRecall of comparison
.... fScore Σ0..1decimalF-score
... readCoverage Σ0..1integerAverage number of reads representing a given nucleotide in the reconstructed sequence
... repository Σ0..*BackboneElementExternal repository which contains detailed report related with observedSeq in this resource
.... type Σ1..1codedirectlink | openapi | login | oauth | other
repositoryType (Required)
.... url Σ0..1uriURI of the repository
.... name Σ0..1stringRepository's name
.... datasetId Σ0..1stringId of the dataset that used to call for dataset in repository
.... variantsetId Σ0..1stringId of the variantset that used to call for variantset in repository
.... readsetId Σ0..1stringId of the read
... pointer Σ0..*Reference(Sequence)Pointer to next atomic sequence

doco Documentation for this format

<?xml version="1.0" encoding="UTF-8"?>
<StructureDefinition xmlns="http://hl7.org/fhir">
  <id value="Sequence"/>
  <meta>
    <versionId value="1"/>
    <lastUpdated value="2017-11-28T08:33:57Z"/>
  </meta>
  <text>
    <status value="generated"/>
    <div xmlns="http://www.w3.org/1999/xhtml">
      <table style="border: 0px #F0F0F0 solid font-size: 11px font-family: verdana vertical-align: top" border="0" cellpadding="0" cellspacing="0">
        <tr style="border: 1px #F0F0F0 solid font-size: 11px font-family: verdana vertical-align: top">
          <th style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a title="The logical name of the element" href="formats.html#table">Name</a>
          </th>
          <th style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a title="Information about the use of the element" href="formats.html#table">Flags</a>
          </th>
          <th style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a title="Minimum and Maximum # of times the the element can appear in the instance" href="formats.html#table">Card.</a>
          </th>
          <th style="width: 100px" class="hierarchy">
            <a title="Reference to the type of the element" href="formats.html#table">Type</a>
          </th>
          <th style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a title="Additional information about the element" href="formats.html#table">Description &amp; Constraints</a>
            <span style="float: right">
              <a title="Legend for this format" href="formats.html#table">
                <img alt="doco" style="background-color: inherit"/>
              </a>
            </span>
          </th>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,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" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Resource"/>
            <span title="Sequence : Raw data describing a biological sequence.">Sequence</span>
            <a name="Sequence"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
            <span style="padding: 3px" title="This element has or is affected by some invariants">I</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy"/>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="domainresource.html">DomainResource</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Information about a biological sequence
            <br/>
            <span style="font-style: italic" title="seq-3">+ Only 0 and 1 are valid for coordinateSystem</span>
            <br/>Elements defined in Ancestors:
            <a title="The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes." href="resource.html#Resource">id</a>,
            <a title="The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content may not always be associated with version changes to the resource." href="resource.html#Resource">meta</a>,
            <a title="A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content." href="resource.html#Resource">implicitRules</a>,
            <a title="The base language in which the resource is written." href="resource.html#Resource">language</a>,
            <a title="A human-readable narrative that contains a summary of the resource, and may be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it &quot;clinically safe&quot; for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety." href="domainresource.html#DomainResource">text</a>,
            <a title="These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope." href="domainresource.html#DomainResource">contained</a>,
            <a title="May be used to represent additional information that is not part of the basic definition of the resource. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension." href="domainresource.html#DomainResource">extension</a>,
            <a title="May be used to represent additional information that is not part of the basic definition of the resource, and that modifies the understanding of the element that contains it. Usually modifier elements provide negation or qualification. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions." href="domainresource.html#DomainResource">modifierExtension</a>
          </td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,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" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Data Type"/>
            <span title="Sequence.identifier : A unique identifier for this particular sequence instance. This is a FHIR-defined id.">identifier</span>
            <a name="Sequence.identifier"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..*</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#Identifier">Identifier</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Unique ID for this particular sequence. This is a FHIR-defined id
            <br/>
          </td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.type : Amino Acid Sequence/ DNA Sequence / RNA Sequence.">type</span>
            <a name="Sequence.type"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#code">code</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">aa | dna | rna
            <br/>
            <a title="Type if a sequence -- DNA, RNA, or amino acid sequence" href="valueset-sequence-type.html">sequenceType</a>(
            <a title="Instances are not expected or even encouraged to draw from the specified value set. The value set merely provides examples of the types of concepts intended to be included." href="terminologies.html#example">Example</a>)</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.coordinateSystem : Whether the sequence is numbered starting at 0 (0-based numbering or coordinates, inclusive start, exclusive end) or starting at 1 (1-based numbering, inclusive start and inclusive end).">coordinateSystem</span>
            <a name="Sequence.coordinateSystem"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">1..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#integer">integer</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Base number of coordinate system (0 for 0-based numbering or coordinates, inclusive start, exclusive end, 1 for 1-based numbering, inclusive start, inclusive end)</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAAAXNSR0IArs4c6QAAAARnQU1BAACxjwv8YQUAAAAJcEhZcwAADsMAAA7DAcdvqGQAAAAadEVYdFNvZnR3YXJlAFBhaW50Lk5FVCB2My41LjEwMPRyoQAAAFxJREFUOE/NjEEOACEIA/0o/38GGw+agoXYeNnDJDCUDnd/gkoFKhWozJiZI3gLwY6rAgxhsPKTPUzycTl8lAryMyMsVQG6TFi6cHULyz8KOjC7OIQKlQpU3uPjAwhX2CCcGsgOAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Reference to another Resource"/>
            <span title="Sequence.patient : The patient whose sequencing results are described by this resource.">patient</span>
            <a name="Sequence.patient"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="references.html">Reference</a>(
            <a href="patient.html">Patient</a>)</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Who and/or what this is about</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAAAXNSR0IArs4c6QAAAARnQU1BAACxjwv8YQUAAAAJcEhZcwAADsMAAA7DAcdvqGQAAAAadEVYdFNvZnR3YXJlAFBhaW50Lk5FVCB2My41LjEwMPRyoQAAAFxJREFUOE/NjEEOACEIA/0o/38GGw+agoXYeNnDJDCUDnd/gkoFKhWozJiZI3gLwY6rAgxhsPKTPUzycTl8lAryMyMsVQG6TFi6cHULyz8KOjC7OIQKlQpU3uPjAwhX2CCcGsgOAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Reference to another Resource"/>
            <span title="Sequence.specimen : Specimen used for sequencing.">specimen</span>
            <a name="Sequence.specimen"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="references.html">Reference</a>(
            <a href="specimen.html">Specimen</a>)</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Specimen used for sequencing</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAAAXNSR0IArs4c6QAAAARnQU1BAACxjwv8YQUAAAAJcEhZcwAADsMAAA7DAcdvqGQAAAAadEVYdFNvZnR3YXJlAFBhaW50Lk5FVCB2My41LjEwMPRyoQAAAFxJREFUOE/NjEEOACEIA/0o/38GGw+agoXYeNnDJDCUDnd/gkoFKhWozJiZI3gLwY6rAgxhsPKTPUzycTl8lAryMyMsVQG6TFi6cHULyz8KOjC7OIQKlQpU3uPjAwhX2CCcGsgOAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Reference to another Resource"/>
            <span title="Sequence.device : The method for sequencing, for example, chip information.">device</span>
            <a name="Sequence.device"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="references.html">Reference</a>(
            <a href="device.html">Device</a>)</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">The method for sequencing</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAAAXNSR0IArs4c6QAAAARnQU1BAACxjwv8YQUAAAAJcEhZcwAADsMAAA7DAcdvqGQAAAAadEVYdFNvZnR3YXJlAFBhaW50Lk5FVCB2My41LjEwMPRyoQAAAFxJREFUOE/NjEEOACEIA/0o/38GGw+agoXYeNnDJDCUDnd/gkoFKhWozJiZI3gLwY6rAgxhsPKTPUzycTl8lAryMyMsVQG6TFi6cHULyz8KOjC7OIQKlQpU3uPjAwhX2CCcGsgOAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Reference to another Resource"/>
            <span title="Sequence.performer : The organization or lab that should be responsible for this result.">performer</span>
            <a name="Sequence.performer"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="references.html">Reference</a>(
            <a href="organization.html">Organization</a>)</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Who should be responsible for test result</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,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" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Data Type"/>
            <span title="Sequence.quantity : The number of copies of the seqeunce of interest. (RNASeq).">quantity</span>
            <a name="Sequence.quantity"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#Quantity">Quantity</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">The number of copies of the seqeunce of interest. (RNASeq)</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,R0lGODlhEAAQAMQfAOvGUf7ztuvPMf/78/fkl/Pbg+u8Rvjqteu2Pf3zxPz36Pz0z+vTmPzurPvuw/npofbjquvNefHVduuyN+uuMu3Oafbgjfnqvf/3zv/3xevPi+vRjP/20/bmsP///////yH5BAEAAB8ALAAAAAAQABAAAAV24CeOZGmepqeqqOgxjBZFa+19r4ftWQUAgqDgltthMshMIJAZ4jYDHsBARSAmFOJvq+g6HIdEFgcYmBWNxoNAsDjGHgBnmV5bCoUDHLBIq9sFEhIdcAYJdYASFRUQhQkLCwkOFwcdEBAXhVabE52ecDahKy0oIQA7" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Element"/>
            <span title="Sequence.referenceSeq : A sequence that is used as a reference to describe variants that are present in a sequence analyzed.">referenceSeq</span>
            <a name="Sequence.referenceSeq"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
            <span style="padding: 3px" title="This element has or is affected by some invariants">I</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="backboneelement.html">BackboneElement</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">A sequence used as reference
            <br/>
            <span style="font-style: italic" title="seq-4">+ Only +1 and -1 are valid for strand</span>
            <br/>
            <span style="font-style: italic" title="seq-5">+ GenomeBuild and chromosome must be both contained if either one of them is contained</span>
            <br/>
            <span style="font-style: italic" title="seq-6">+ Have and only have one of the following elements in referenceSeq : 1. genomeBuild 2 referenceSeqId 3. referenceSeqPointer 4. referenceSeqString</span>
          </td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,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" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Data Type"/>
            <span title="Sequence.referenceSeq.chromosome : Structural unit composed of a nucleic acid molecule which controls its own replication through the interaction of specific proteins at one or more origins of replication ([SO:0000340](http://www.sequenceontology.org/browser/current_svn/term/SO:0000340)).">chromosome</span>
            <a name="Sequence.referenceSeq.chromosome"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Chromosome containing genetic finding
            <br/>
            <a title="Chromosome number for human" href="valueset-chromosome-human.html">chromosome-human</a>(
            <a title="Instances are not expected or even encouraged to draw from the specified value set. The value set merely provides examples of the types of concepts intended to be included." href="terminologies.html#example">Example</a>)</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.referenceSeq.genomeBuild : The Genome Build used for reference, following GRCh build versions e.g. &apos;GRCh 37&apos;. Version number must be included if a versioned release of a primary build was used.">genomeBuild</span>
            <a name="Sequence.referenceSeq.genomeBuild"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#string">string</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">The Genome Build used for reference, following GRCh build versions e.g. 'GRCh 37'</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,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" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Data Type"/>
            <span title="Sequence.referenceSeq.referenceSeqId : Reference identifier of reference sequence submitted to NCBI. It must match the type in the Sequence.type field. For example, the prefix, &#8220;NG_&#8221; identifies reference sequence for genes, &#8220;NM_&#8221; for messenger RNA transcripts, and &#8220;NP_&#8221; for amino acid sequences.">referenceSeqId</span>
            <a name="Sequence.referenceSeq.referenceSeqId"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Reference identifier
            <br/>
            <a title="Reference identifier" href="valueset-sequence-referenceSeq.html">ENSEMBL</a>(
            <a title="Instances are not expected or even encouraged to draw from the specified value set. The value set merely provides examples of the types of concepts intended to be included." href="terminologies.html#example">Example</a>)</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAAAXNSR0IArs4c6QAAAARnQU1BAACxjwv8YQUAAAAJcEhZcwAADsMAAA7DAcdvqGQAAAAadEVYdFNvZnR3YXJlAFBhaW50Lk5FVCB2My41LjEwMPRyoQAAAFxJREFUOE/NjEEOACEIA/0o/38GGw+agoXYeNnDJDCUDnd/gkoFKhWozJiZI3gLwY6rAgxhsPKTPUzycTl8lAryMyMsVQG6TFi6cHULyz8KOjC7OIQKlQpU3uPjAwhX2CCcGsgOAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Reference to another Resource"/>
            <span title="Sequence.referenceSeq.referenceSeqPointer : A Pointer to another Sequence entity as reference sequence.">referenceSeqPointer</span>
            <a name="Sequence.referenceSeq.referenceSeqPointer"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="references.html">Reference</a>(
            <a href="sequence.html">Sequence</a>)</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">A Pointer to another Sequence entity as reference sequence</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.referenceSeq.referenceSeqString : A string like &quot;ACGT&quot;.">referenceSeqString</span>
            <a name="Sequence.referenceSeq.referenceSeqString"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#string">string</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">A string to represent reference sequence</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.referenceSeq.strand : Directionality of DNA sequence. Available values are &quot;1&quot; for the plus strand (5&apos; to 3&apos;)/Watson/Sense/positive and &quot;-1&quot; for the minus strand(3&apos; to 5&apos;)/Crick/Antisense/negative.">strand</span>
            <a name="Sequence.referenceSeq.strand"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#integer">integer</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Directionality of DNA ( +1/-1)</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.referenceSeq.windowStart : Start position of the window on the reference sequence. If the coordinate system is either 0-based or 1-based, then start position is inclusive.">windowStart</span>
            <a name="Sequence.referenceSeq.windowStart"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">1..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#integer">integer</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Start position of the window on the reference sequence</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzME+lXFigAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+3OsRUAIAjEUOL+O8cJABttJM11/x1qZAGqRBEVcNIqdWj1efDqQbb3HwwwwEfABmQUHSPM9dtDAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.referenceSeq.windowEnd : End position of the window on the reference sequence. If the coordinate system is 0-based then end is is exclusive and does not include the last position. If the coordinate system is 1-base, then end is inclusive and includes the last position.">windowEnd</span>
            <a name="Sequence.referenceSeq.windowEnd"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">1..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#integer">integer</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">End position of the window on the reference sequence</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,R0lGODlhEAAQAMQfAOvGUf7ztuvPMf/78/fkl/Pbg+u8Rvjqteu2Pf3zxPz36Pz0z+vTmPzurPvuw/npofbjquvNefHVduuyN+uuMu3Oafbgjfnqvf/3zv/3xevPi+vRjP/20/bmsP///////yH5BAEAAB8ALAAAAAAQABAAAAV24CeOZGmepqeqqOgxjBZFa+19r4ftWQUAgqDgltthMshMIJAZ4jYDHsBARSAmFOJvq+g6HIdEFgcYmBWNxoNAsDjGHgBnmV5bCoUDHLBIq9sFEhIdcAYJdYASFRUQhQkLCwkOFwcdEBAXhVabE52ecDahKy0oIQA7" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Element"/>
            <span title="Sequence.variant : The definition of variant here originates from Sequence ontology ([variant_of](http://www.sequenceontology.org/browser/current_svn/term/variant_of)). This element can represent amino acid or nucleic sequence change(including insertion,deletion,SNP,etc.) It can represent some complex mutation or segment variation with the assist of CIGAR string.">variant</span>
            <a name="Sequence.variant"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..*</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="backboneelement.html">BackboneElement</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Variant in sequence
            <br/>
          </td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.variant.start : Start position of the variant on the reference sequence.If the coordinate system is either 0-based or 1-based, then start position is inclusive.">start</span>
            <a name="Sequence.variant.start"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#integer">integer</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Start position of the variant on the reference sequence</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.variant.end : End position of the variant on the reference sequence.If the coordinate system is 0-based then end is is exclusive and does not include the last position. If the coordinate system is 1-base, then end is inclusive and includes the last position.">end</span>
            <a name="Sequence.variant.end"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#integer">integer</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">End position of the variant on the reference sequence</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.variant.observedAllele : An allele is one of a set of coexisting sequence variants of a gene ([SO:0001023](http://www.sequenceontology.org/browser/current_svn/term/SO:0001023)). Nucleotide(s)/amino acids from start position of sequence to stop position of sequence on the positive (+) strand of the observed sequence. When the sequence type is DNA, it should be the sequence on the positive (+) strand. This will lay in the range between variant.start and variant.end.">observedAllele</span>
            <a name="Sequence.variant.observedAllele"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#string">string</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Allele that was observed</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.variant.referenceAllele : An allele is one of a set of coexisting sequence variants of a gene ([SO:0001023](http://www.sequenceontology.org/browser/current_svn/term/SO:0001023)). Nucleotide(s)/amino acids from start position of sequence to stop position of sequence on the positive (+) strand of the reference sequence. When the sequence type is DNA, it should be the sequence on the positive (+) strand. This will lay in the range between variant.start and variant.end.">referenceAllele</span>
            <a name="Sequence.variant.referenceAllele"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#string">string</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Allele in the reference sequence</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.variant.cigar : Extended CIGAR string for aligning the sequence with reference bases. See detailed documentation [here](http://support.illumina.com/help/SequencingAnalysisWorkflow/Content/Vault/Informatics/Sequencing_Analysis/CASAVA/swSEQ_mCA_ExtendedCIGARFormat.htm).">cigar</span>
            <a name="Sequence.variant.cigar"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#string">string</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Extended CIGAR string for aligning the sequence with reference bases</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzME+lXFigAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+3OsRUAIAjEUOL+O8cJABttJM11/x1qZAGqRBEVcNIqdWj1efDqQbb3HwwwwEfABmQUHSPM9dtDAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAAAXNSR0IArs4c6QAAAARnQU1BAACxjwv8YQUAAAAJcEhZcwAADsMAAA7DAcdvqGQAAAAadEVYdFNvZnR3YXJlAFBhaW50Lk5FVCB2My41LjEwMPRyoQAAAFxJREFUOE/NjEEOACEIA/0o/38GGw+agoXYeNnDJDCUDnd/gkoFKhWozJiZI3gLwY6rAgxhsPKTPUzycTl8lAryMyMsVQG6TFi6cHULyz8KOjC7OIQKlQpU3uPjAwhX2CCcGsgOAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Reference to another Resource"/>
            <span title="Sequence.variant.variantPointer : A pointer to an Observation containing variant information.">variantPointer</span>
            <a name="Sequence.variant.variantPointer"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="references.html">Reference</a>(
            <a href="observation.html">Observation</a>)</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Pointer to observed variant information</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.observedSeq : Sequence that was observed. It is the result marked by referenceSeq along with variant records on referenceSeq. This shall starts from referenceSeq.windowStart and end by referenceSeq.windowEnd.">observedSeq</span>
            <a name="Sequence.observedSeq"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#string">string</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Sequence that was observed</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,R0lGODlhEAAQAMQfAOvGUf7ztuvPMf/78/fkl/Pbg+u8Rvjqteu2Pf3zxPz36Pz0z+vTmPzurPvuw/npofbjquvNefHVduuyN+uuMu3Oafbgjfnqvf/3zv/3xevPi+vRjP/20/bmsP///////yH5BAEAAB8ALAAAAAAQABAAAAV24CeOZGmepqeqqOgxjBZFa+19r4ftWQUAgqDgltthMshMIJAZ4jYDHsBARSAmFOJvq+g6HIdEFgcYmBWNxoNAsDjGHgBnmV5bCoUDHLBIq9sFEhIdcAYJdYASFRUQhQkLCwkOFwcdEBAXhVabE52ecDahKy0oIQA7" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Element"/>
            <span title="Sequence.quality : An experimental feature attribute that defines the quality of the feature in a quantitative way, such as a phred quality score ([SO:0001686](http://www.sequenceontology.org/browser/current_svn/term/SO:0001686)).">quality</span>
            <a name="Sequence.quality"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..*</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="backboneelement.html">BackboneElement</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">An set of value as quality of sequence
            <br/>
          </td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.quality.type : INDEL / SNP / Undefined variant.">type</span>
            <a name="Sequence.quality.type"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">1..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#code">code</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">indel | snp | unknown
            <br/>
            <a title="Type for quality report" href="valueset-quality-type.html">qualityType</a>(
            <a title="To be conformant, the concept in this element SHALL be from the specified value set" href="terminologies.html#required">Required</a>)</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,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" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Data Type"/>
            <span title="Sequence.quality.standardSequence : Gold standard sequence used for comparing against.">standardSequence</span>
            <a name="Sequence.quality.standardSequence"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Standard sequence for comparison
            <br/>
            <a title="Reference identifier of the sequence that used to mark the quality of tested samples." href="valueset-sequence-quality-standardSequence.html">FDA-StandardSequence</a>(
            <a title="Instances are not expected or even encouraged to draw from the specified value set. The value set merely provides examples of the types of concepts intended to be included." href="terminologies.html#example">Example</a>)</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.quality.start : Start position of the sequence. If the coordinate system is either 0-based or 1-based, then start position is inclusive.">start</span>
            <a name="Sequence.quality.start"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#integer">integer</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Start position of the sequence</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.quality.end : End position of the sequence.If the coordinate system is 0-based then end is is exclusive and does not include the last position. If the coordinate system is 1-base, then end is inclusive and includes the last position.">end</span>
            <a name="Sequence.quality.end"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#integer">integer</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">End position of the sequence</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,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" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Data Type"/>
            <span title="Sequence.quality.score : The score of an experimentally derived feature such as a p-value ([SO:0001685](http://www.sequenceontology.org/browser/current_svn/term/SO:0001685)).">score</span>
            <a name="Sequence.quality.score"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#Quantity">Quantity</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Quality score for the comparison</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,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" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Data Type"/>
            <span title="Sequence.quality.method : Which method is used to get sequence quality.">method</span>
            <a name="Sequence.quality.method"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#CodeableConcept">CodeableConcept</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Method to get quality
            <br/>
            <a title="The method used to evaluate the numerical quality of the observed sequence." href="valueset-sequence-quality-method.html">FDA-Method</a>(
            <a title="Instances are not expected or even encouraged to draw from the specified value set. The value set merely provides examples of the types of concepts intended to be included." href="terminologies.html#example">Example</a>)</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.quality.truthTP : True positives, from the perspective of the truth data, i.e. the number of sites in the Truth Call Set for which there are paths through the Query Call Set that are consistent with all of the alleles at this site, and for which there is an accurate genotype call for the event.">truthTP</span>
            <a name="Sequence.quality.truthTP"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#decimal">decimal</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">True positives from the perspective of the truth data</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.quality.queryTP : True positives, from the perspective of the query data, i.e. the number of sites in the Query Call Set for which there are paths through the Truth Call Set that are consistent with all of the alleles at this site, and for which there is an accurate genotype call for the event.">queryTP</span>
            <a name="Sequence.quality.queryTP"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#decimal">decimal</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">True positives from the perspective of the query data</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.quality.truthFN : False negatives, i.e. the number of sites in the Truth Call Set for which there is no path through the Query Call Set that is consistent with all of the alleles at this site, or sites for which there is an inaccurate genotype call for the event. Sites with correct variant but incorrect genotype are counted here.">truthFN</span>
            <a name="Sequence.quality.truthFN"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#decimal">decimal</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">False negatives</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.quality.queryFP : False positives, i.e. the number of sites in the Query Call Set for which there is no path through the Truth Call Set that is consistent with this site. Sites with correct variant but incorrect genotype are counted here.">queryFP</span>
            <a name="Sequence.quality.queryFP"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#decimal">decimal</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">False positives</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.quality.gtFP : The number of false positives where the non-REF alleles in the Truth and Query Call Sets match (i.e. cases where the truth is 1/1 and the query is 0/1 or similar).">gtFP</span>
            <a name="Sequence.quality.gtFP"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#decimal">decimal</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">False positives where the non-REF alleles in the Truth and Query Call Sets match</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.quality.precision : QUERY.TP / (QUERY.TP + QUERY.FP).">precision</span>
            <a name="Sequence.quality.precision"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#decimal">decimal</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Precision of comparison</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.quality.recall : TRUTH.TP / (TRUTH.TP + TRUTH.FN).">recall</span>
            <a name="Sequence.quality.recall"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#decimal">decimal</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Recall of comparison</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzME+lXFigAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+3OsRUAIAjEUOL+O8cJABttJM11/x1qZAGqRBEVcNIqdWj1efDqQbb3HwwwwEfABmQUHSPM9dtDAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.quality.fScore : Harmonic mean of Recall and Precision, computed as: 2 * precision * recall / (precision + recall).">fScore</span>
            <a name="Sequence.quality.fScore"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#decimal">decimal</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">F-score</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.readCoverage : Coverage (read depth or depth) is the average number of reads representing a given nucleotide in the reconstructed sequence.">readCoverage</span>
            <a name="Sequence.readCoverage"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#integer">integer</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Average number of reads representing a given nucleotide in the reconstructed sequence</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,R0lGODlhEAAQAMQfAOvGUf7ztuvPMf/78/fkl/Pbg+u8Rvjqteu2Pf3zxPz36Pz0z+vTmPzurPvuw/npofbjquvNefHVduuyN+uuMu3Oafbgjfnqvf/3zv/3xevPi+vRjP/20/bmsP///////yH5BAEAAB8ALAAAAAAQABAAAAV24CeOZGmepqeqqOgxjBZFa+19r4ftWQUAgqDgltthMshMIJAZ4jYDHsBARSAmFOJvq+g6HIdEFgcYmBWNxoNAsDjGHgBnmV5bCoUDHLBIq9sFEhIdcAYJdYASFRUQhQkLCwkOFwcdEBAXhVabE52ecDahKy0oIQA7" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Element"/>
            <span title="Sequence.repository : Configurations of the external repository. The repository shall store target&apos;s observedSeq or records related with target&apos;s observedSeq.">repository</span>
            <a name="Sequence.repository"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..*</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="backboneelement.html">BackboneElement</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">External repository which contains detailed report related with observedSeq in this resource
            <br/>
          </td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.repository.type : Click and see / RESTful API / Need login to see / RESTful API with authentication / Other ways to see resource.">type</span>
            <a name="Sequence.repository.type"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">1..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#code">code</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">directlink | openapi | login | oauth | other
            <br/>
            <a title="Type for access of external URI" href="valueset-repository-type.html">repositoryType</a>(
            <a title="To be conformant, the concept in this element SHALL be from the specified value set" href="terminologies.html#required">Required</a>)</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.repository.url : URI of an external repository which contains further details about the genetics data.">url</span>
            <a name="Sequence.repository.url"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#uri">uri</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">URI of the repository</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.repository.name : URI of an external repository which contains further details about the genetics data.">name</span>
            <a name="Sequence.repository.name"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#string">string</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Repository's name</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.repository.datasetId : Id of the variant in this external repository. The server will understand how to use this id to call for more info about datasets in external repository.">datasetId</span>
            <a name="Sequence.repository.datasetId"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#string">string</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Id of the dataset that used to call for dataset in repository</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAMElEQVR42u3QwQkAMAwDsezq/WdoskKgFAoy6HkfV5LamJ1tc7MHAAD+5QQAAOCZBkurQFbnaRSlAAAAAElFTkSuQmCC)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzI3XJ6V3QAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+2RsQ0AIAzDav7/2VzQwoCY4iWbZSmo1QGoUgNMghvWaIejPQW/CrrNCylIwcOCDYfLNRcNer4SAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.repository.variantsetId : Id of the variantset in this external repository. The server will understand how to use this id to call for more info about variantsets in external repository.">variantsetId</span>
            <a name="Sequence.repository.variantsetId"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#string">string</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Id of the variantset that used to call for variantset in repository</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAL0lEQVR42u3XsQ0AQAgCQHdl/xn8jxvYWB3JlTR0VJLa+OltBwAAYP6EEQAAgCsPVYVAgIJrA/sAAAAASUVORK5CYII=)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzMPbYccAgAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAMElEQVQ4y+3OQREAIBDDwAv+PQcFFN5MIyCzqHMKUGVCpMFLK97heq+gggoq+EiwAVjvMhFGmlEUAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzME+lXFigAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+3OsRUAIAjEUOL+O8cJABttJM11/x1qZAGqRBEVcNIqdWj1efDqQbb3HwwwwEfABmQUHSPM9dtDAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAABmJLR0QA/wD/AP+gvaeTAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3gYBFzI0BrFQCwAAAERJREFUOMtj/P//PwMlgImBQjDwBrCcOnWKokBgYWBgYDCU+06W5i8MUggvnH/EOVJjAW4AuQHJ+O75LYqikXE0LzAAALePEntTkEoSAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Primitive Data Type"/>
            <span title="Sequence.repository.readsetId : Id of the read in this external repository.">readsetId</span>
            <a name="Sequence.repository.readsetId"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..1</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="datatypes.html#string">string</a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Id of the read</td>
        </tr>
        <tr style="border: 0px #F0F0F0 solid padding:0px vertical-align: top background-color: white">
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px white-space: nowrap background-image: url(data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAyAAAAACCAYAAACg/LjIAAAAI0lEQVR42u3QIQEAAAACIL/6/4MvTAQOkLYBAAB4kAAAANwMad9AqkRjgNAAAAAASUVORK5CYII=)" class="hierarchy">
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAAAEAAAAWCAYAAAABxvaqAAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzIs1vtcMQAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAAE0lEQVQI12P4//8/AxMDAwNdCABMPwMo2ctnoQAAAABJRU5ErkJggg==" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAWCAYAAADJqhx8AAAACXBIWXMAAAsTAAALEwEAmpwYAAAAB3RJTUUH3wYeFzME+lXFigAAAB1pVFh0Q29tbWVudAAAAAAAQ3JlYXRlZCB3aXRoIEdJTVBkLmUHAAAANklEQVQ4y+3OsRUAIAjEUOL+O8cJABttJM11/x1qZAGqRBEVcNIqdWj1efDqQbb3HwwwwEfABmQUHSPM9dtDAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: inherit"/>
            <img src="data: image/pngbase64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAAAAXNSR0IArs4c6QAAAARnQU1BAACxjwv8YQUAAAAJcEhZcwAADsMAAA7DAcdvqGQAAAAadEVYdFNvZnR3YXJlAFBhaW50Lk5FVCB2My41LjEwMPRyoQAAAFxJREFUOE/NjEEOACEIA/0o/38GGw+agoXYeNnDJDCUDnd/gkoFKhWozJiZI3gLwY6rAgxhsPKTPUzycTl8lAryMyMsVQG6TFi6cHULyz8KOjC7OIQKlQpU3uPjAwhX2CCcGsgOAAAAAElFTkSuQmCC" class="hierarchy" alt="." style="background-color: white background-color: inherit" title="Reference to another Resource"/>
            <span title="Sequence.pointer : Pointer to next atomic sequence which at most contains one variant.">pointer</span>
            <a name="Sequence.pointer"> </a>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <span style="padding: 3px" title="This element is included in summaries">&#931;</span>
          </td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">0..*</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">
            <a href="references.html">Reference</a>(
            <a href="sequence.html">Sequence</a>)</td>
          <td style="vertical-align: top text-align : left background-color: white border: 0px #F0F0F0 solid padding:0px 4px 0px 4px" class="hierarchy">Pointer to next atomic sequence
            <br/>
          </td>
        </tr>
        <tr>
          <td colspan="5" class="hierarchy">
            <br/>
            <a title="Legend for this format" href="formats.html#table">
              <img alt="doco" style="background-color: inherit"/>Documentation for this format</a>
          </td>
        </tr>
      </table>
    </div>
  </text>
  <extension url="http://localhost/StructureDefinition/structuredefinition-fmm">
    <valueInteger value="1"/>
  </extension>
  <extension url="http://localhost/StructureDefinition/structuredefinition-wg">
    <valueCode value="cg"/>
  </extension>
  <url value="http://hl7.org/fhir/StructureDefinition/Sequence"/>
  <name value="Sequence"/>
  <status value="draft"/>
  <date value="2017-04-27T17:09:41+10:00"/>
  <publisher value="Health Level Seven International (Clinical Genomics)"/>
  <contact>
    <telecom>
      <system value="url"/>
      <value value="http://hl7.org/fhir"/>
    </telecom>
  </contact>
  <contact>
    <telecom>
      <system value="url"/>
      <value value="http://www.hl7.org/Special/committees/clingenomics/index.cfm"/>
    </telecom>
  </contact>
  <description value="Raw data describing a biological sequence."/>
  <fhirVersion value="3.0.1"/>
  <mapping>
    <identity value="w5"/>
    <uri value="http://hl7.org/fhir/w5"/>
    <name value="W5 Mapping"/>
  </mapping>
  <mapping>
    <identity value="rim"/>
    <uri value="http://hl7.org/v3"/>
    <name value="RIM Mapping"/>
  </mapping>
  <kind value="resource"/>
  <abstract value="false"/>
  <type value="Sequence"/>
  <baseDefinition value="http://hl7.org/fhir/StructureDefinition/DomainResource"/>
  <derivation value="specialization"/>
  <snapshot>
    <element id="Sequence">
      <path value="Sequence"/>
      <short value="Information about a biological sequence"/>
      <definition value="Raw data describing a biological sequence."/>
      <min value="0"/>
      <max value="*"/>
      <constraint>
        <key value="dom-2"/>
        <severity value="error"/>
        <human value="If the resource is contained in another resource, it SHALL NOT contain nested Resources"/>
        <expression value="contained.contained.empty()"/>
        <xpath value="not(parent::f:contained and f:contained)"/>
        <source value="DomainResource"/>
      </constraint>
      <constraint>
        <key value="dom-1"/>
        <severity value="error"/>
        <human value="If the resource is contained in another resource, it SHALL NOT contain any narrative"/>
        <expression value="contained.text.empty()"/>
        <xpath value="not(parent::f:contained and f:text)"/>
        <source value="DomainResource"/>
      </constraint>
      <constraint>
        <key value="dom-4"/>
        <severity value="error"/>
        <human value="If a resource is contained in another resource, it SHALL NOT have a meta.versionId or a meta.lastUpdated"/>
        <expression value="contained.meta.versionId.empty() and contained.meta.lastUpdated.empty()"/>
        <xpath value="not(exists(f:contained/*/f:meta/f:versionId)) and not(exists(f:contained/*/f:meta/f:lastUpdated))"/>
        <source value="DomainResource"/>
      </constraint>
      <constraint>
        <key value="dom-3"/>
        <severity value="error"/>
        <human value="If the resource is contained in another resource, it SHALL be referred to from elsewhere in the resource"/>
        <expression value="contained.where((&apos;#&apos;+id in %resource.descendants().reference).not()).empty()"/>
        <xpath value="not(exists(for $id in f:contained/*/@id return $id[not(ancestor::f:contained/parent::*/descendant::f:reference/@value=concat(&apos;#&apos;, $id))]))"/>
        <source value="DomainResource"/>
      </constraint>
      <constraint>
        <key value="seq-3"/>
        <severity value="error"/>
        <human value="Only 0 and 1 are valid for coordinateSystem"/>
        <expression value="coordinateSystem = 1 or coordinateSystem = 0"/>
        <xpath value="count(f:coordinateSystem[@value=0 and @value=1]) = 1"/>
      </constraint>
      <mapping>
        <identity value="rim"/>
        <map value="Entity. Role, or Act"/>
      </mapping>
      <mapping>
        <identity value="w5"/>
        <map value="clinical.diagnostics"/>
      </mapping>
    </element>
    <element id="Sequence.id">
      <path value="Sequence.id"/>
      <short value="Logical id of this artifact"/>
      <definition value="The logical id of the resource, as used in the URL for the resource. Once assigned, this value never changes."/>
      <comment value="The only time that a resource does not have an id is when it is being submitted to the server using a create operation."/>
      <min value="0"/>
      <max value="1"/>
      <base>
        <path value="Resource.id"/>
        <min value="0"/>
        <max value="1"/>
      </base>
      <type>
        <code value="id"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.meta">
      <path value="Sequence.meta"/>
      <short value="Metadata about the resource"/>
      <definition value="The metadata about the resource. This is content that is maintained by the infrastructure. Changes to the content may not always be associated with version changes to the resource."/>
      <min value="0"/>
      <max value="1"/>
      <base>
        <path value="Resource.meta"/>
        <min value="0"/>
        <max value="1"/>
      </base>
      <type>
        <code value="Meta"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.implicitRules">
      <path value="Sequence.implicitRules"/>
      <short value="A set of rules under which this content was created"/>
      <definition value="A reference to a set of rules that were followed when the resource was constructed, and which must be understood when processing the content."/>
      <comment value="Asserting this rule set restricts the content to be only understood by a limited set of trading partners. This inherently limits the usefulness of the data in the long term. However, the existing health eco-system is highly fractured, and not yet ready to define, collect, and exchange data in a generally computable sense. Wherever possible, implementers and/or specification writers should avoid using this element. &#10;&#10;This element is labelled as a modifier because the implicit rules may provide additional knowledge about the resource that modifies it&apos;s meaning or interpretation."/>
      <min value="0"/>
      <max value="1"/>
      <base>
        <path value="Resource.implicitRules"/>
        <min value="0"/>
        <max value="1"/>
      </base>
      <type>
        <code value="uri"/>
      </type>
      <isModifier value="false"/>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.language">
      <path value="Sequence.language"/>
      <short value="Language of the resource content"/>
      <definition value="The base language in which the resource is written."/>
      <comment value="Language is provided to support indexing and accessibility (typically, services such as text to speech use the language tag). The html language tag in the narrative applies to the narrative. The language tag on the resource may be used to specify the language of other presentations generated from the data in the resource Not all the content has to be in the base language. The Resource.language should not be assumed to apply to the narrative automatically. If a language is specified, it should it also be specified on the div element in the html (see rules in HTML5 for information about the relationship between xml:lang and the html lang attribute)."/>
      <min value="0"/>
      <max value="1"/>
      <base>
        <path value="Resource.language"/>
        <min value="0"/>
        <max value="1"/>
      </base>
      <type>
        <code value="code"/>
      </type>
      <binding>
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-maxValueSet">
          <valueReference>
            <reference value="http://hl7.org/fhir/ValueSet/all-languages"/>
          </valueReference>
        </extension>
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="Language"/>
        </extension>
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-isCommonBinding">
          <valueBoolean value="false"/>
        </extension>
        <strength value="extensible"/>
        <description value="A human language."/>
        <valueSetReference>
          <reference value="http://hl7.org/fhir/ValueSet/languages"/>
        </valueSetReference>
      </binding>
    </element>
    <element id="Sequence.text">
      <path value="Sequence.text"/>
      <short value="Text summary of the resource, for human interpretation"/>
      <definition value="A human-readable narrative that contains a summary of the resource, and may be used to represent the content of the resource to a human. The narrative need not encode all the structured data, but is required to contain sufficient detail to make it &quot;clinically safe&quot; for a human to just read the narrative. Resource definitions may define what content should be represented in the narrative to ensure clinical safety."/>
      <comment value="Contained resources do not have narrative. Resources that are not contained SHOULD have a narrative. In some cases, a resource may only have text with little or no additional discrete data (as long as all minOccurs=1 elements are satisfied). This may be necessary for data from legacy systems where information is captured as a &quot;text blob&quot; or where text is additionally entered raw or narrated and encoded in formation is added later."/>
      <alias value="narrative"/>
      <alias value="html"/>
      <alias value="xhtml"/>
      <alias value="display"/>
      <min value="0"/>
      <max value="1"/>
      <base>
        <path value="DomainResource.text"/>
        <min value="0"/>
        <max value="1"/>
      </base>
      <type>
        <code value="Narrative"/>
      </type>
      <condition value="dom-1"/>
      <mapping>
        <identity value="rim"/>
        <map value="Act.text?"/>
      </mapping>
    </element>
    <element id="Sequence.contained">
      <path value="Sequence.contained"/>
      <short value="Contained, inline Resources"/>
      <definition value="These resources do not have an independent existence apart from the resource that contains them - they cannot be identified independently, and nor can they have their own independent transaction scope."/>
      <comment value="This should never be done when the content can be identified properly, as once identification is lost, it is extremely difficult (and context dependent) to restore it again."/>
      <alias value="inline resources"/>
      <alias value="anonymous resources"/>
      <alias value="contained resources"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="DomainResource.contained"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="Resource"/>
      </type>
      <mapping>
        <identity value="rim"/>
        <map value="N/A"/>
      </mapping>
    </element>
    <element id="Sequence.extension">
      <path value="Sequence.extension"/>
      <short value="Additional Content defined by implementations"/>
      <definition value="May be used to represent additional information that is not part of the basic definition of the resource. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension."/>
      <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone."/>
      <alias value="extensions"/>
      <alias value="user content"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="DomainResource.extension"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="Extension"/>
      </type>
      <mapping>
        <identity value="rim"/>
        <map value="N/A"/>
      </mapping>
    </element>
    <element id="Sequence.modifierExtension">
      <path value="Sequence.modifierExtension"/>
      <short value="Extensions that cannot be ignored"/>
      <definition value="May be used to represent additional information that is not part of the basic definition of the resource, and that modifies the understanding of the element that contains it. Usually modifier elements provide negation or qualification. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions."/>
      <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone."/>
      <alias value="extensions"/>
      <alias value="user content"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="DomainResource.modifierExtension"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="Extension"/>
      </type>
      <isModifier value="false"/>
      <mapping>
        <identity value="rim"/>
        <map value="N/A"/>
      </mapping>
    </element>
    <element id="Sequence.identifier">
      <path value="Sequence.identifier"/>
      <short value="Unique ID for this particular sequence. This is a FHIR-defined id"/>
      <definition value="A unique identifier for this particular sequence instance. This is a FHIR-defined id."/>
      <requirements value="Allows sequences to be distinguished and referenced."/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="Identifier"/>
      </type>
      <isSummary value="false"/>
      <mapping>
        <identity value="w5"/>
        <map value="id"/>
      </mapping>
    </element>
    <element id="Sequence.type">
      <path value="Sequence.type"/>
      <short value="aa | dna | rna"/>
      <definition value="Amino Acid Sequence/ DNA Sequence / RNA Sequence."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="code"/>
      </type>
      <isSummary value="false"/>
      <binding>
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="sequenceType"/>
        </extension>
        <strength value="example"/>
        <description value="Type if a sequence -- DNA, RNA, or amino acid sequence"/>
        <valueSetReference>
          <reference value="http://hl7.org/fhir/ValueSet/sequence-type"/>
        </valueSetReference>
      </binding>
    </element>
    <element id="Sequence.coordinateSystem">
      <path value="Sequence.coordinateSystem"/>
      <short value="Base number of coordinate system (0 for 0-based numbering or coordinates, inclusive start, exclusive end, 1 for 1-based numbering, inclusive start, inclusive end)"/>
      <definition value="Whether the sequence is numbered starting at 0 (0-based numbering or coordinates, inclusive start, exclusive end) or starting at 1 (1-based numbering, inclusive start and inclusive end)."/>
      <min value="1"/>
      <max value="1"/>
      <type>
        <code value="integer"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.patient">
      <path value="Sequence.patient"/>
      <short value="Who and/or what this is about"/>
      <definition value="The patient whose sequencing results are described by this resource."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="Reference"/>
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Patient"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.specimen">
      <path value="Sequence.specimen"/>
      <short value="Specimen used for sequencing"/>
      <definition value="Specimen used for sequencing."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="Reference"/>
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Specimen"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.device">
      <path value="Sequence.device"/>
      <short value="The method for sequencing"/>
      <definition value="The method for sequencing, for example, chip information."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="Reference"/>
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Device"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.performer">
      <path value="Sequence.performer"/>
      <short value="Who should be responsible for test result"/>
      <definition value="The organization or lab that should be responsible for this result."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="Reference"/>
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Organization"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quantity">
      <path value="Sequence.quantity"/>
      <short value="The number of copies of the seqeunce of interest. (RNASeq)"/>
      <definition value="The number of copies of the seqeunce of interest. (RNASeq)."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="Quantity"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.referenceSeq">
      <path value="Sequence.referenceSeq"/>
      <short value="A sequence used as reference"/>
      <definition value="A sequence that is used as a reference to describe variants that are present in a sequence analyzed."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="BackboneElement"/>
      </type>
      <constraint>
        <key value="ele-1"/>
        <severity value="error"/>
        <human value="All FHIR elements must have a @value or children"/>
        <expression value="hasValue() | (children().count() &gt; id.count())"/>
        <xpath value="@value|f:*|h:div"/>
        <source value="Element"/>
      </constraint>
      <constraint>
        <key value="seq-4"/>
        <severity value="error"/>
        <human value="Only +1 and -1 are valid for strand"/>
        <expression value="strand.empty() or strand = 1 or strand = -1"/>
        <xpath value="not(exists(f:strand)) or count(f:strand[@value=-1 and @value=1]) = 1"/>
      </constraint>
      <constraint>
        <key value="seq-5"/>
        <severity value="error"/>
        <human value="GenomeBuild and chromosome must be both contained if either one of them is contained"/>
        <expression value="(chromosome.empty() and genomeBuild.empty()) or (chromosome.exists() and genomeBuild.exists())"/>
        <xpath value="(exists(f:chromosome) and exists(f:genomeBuild)) or (not(exists(f:chromosome)) and not(exists(f:genomeBuild)))"/>
      </constraint>
      <constraint>
        <key value="seq-6"/>
        <severity value="error"/>
        <human value="Have and only have one of the following elements in referenceSeq : 1. genomeBuild 2 referenceSeqId 3. referenceSeqPointer 4. referenceSeqString"/>
        <expression value="(genomeBuild.count()+referenceSeqId.count()+ referenceSeqPointer.count()+ referenceSeqString.count()) = 1"/>
        <xpath value="count(f:genomeBuild)+count(f:referenceSeqId)+count(f:referenceSeqPointer)+count(f:referenceSeqString)=1"/>
      </constraint>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.referenceSeq.id">
      <path value="Sequence.referenceSeq.id"/>
      <representation value="xmlAttr"/>
      <short value="xml:id (or equivalent in JSON)"/>
      <definition value="unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces."/>
      <min value="0"/>
      <max value="1"/>
      <base>
        <path value="Element.id"/>
        <min value="0"/>
        <max value="1"/>
      </base>
      <type>
        <code value="string"/>
      </type>
      <mapping>
        <identity value="rim"/>
        <map value="n/a"/>
      </mapping>
    </element>
    <element id="Sequence.referenceSeq.extension">
      <path value="Sequence.referenceSeq.extension"/>
      <short value="Additional Content defined by implementations"/>
      <definition value="May be used to represent additional information that is not part of the basic definition of the element. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension."/>
      <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone."/>
      <alias value="extensions"/>
      <alias value="user content"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Element.extension"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="Extension"/>
      </type>
      <mapping>
        <identity value="rim"/>
        <map value="n/a"/>
      </mapping>
    </element>
    <element id="Sequence.referenceSeq.modifierExtension">
      <path value="Sequence.referenceSeq.modifierExtension"/>
      <short value="Extensions that cannot be ignored"/>
      <definition value="May be used to represent additional information that is not part of the basic definition of the element, and that modifies the understanding of the element that contains it. Usually modifier elements provide negation or qualification. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions."/>
      <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone."/>
      <alias value="extensions"/>
      <alias value="user content"/>
      <alias value="modifiers"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="BackboneElement.modifierExtension"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="Extension"/>
      </type>
      <isModifier value="false"/>
      <isSummary value="false"/>
      <mapping>
        <identity value="rim"/>
        <map value="N/A"/>
      </mapping>
    </element>
    <element id="Sequence.referenceSeq.chromosome">
      <path value="Sequence.referenceSeq.chromosome"/>
      <short value="Chromosome containing genetic finding"/>
      <definition value="Structural unit composed of a nucleic acid molecule which controls its own replication through the interaction of specific proteins at one or more origins of replication ([SO:0000340](http://www.sequenceontology.org/browser/current_svn/term/SO:0000340))."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="CodeableConcept"/>
      </type>
      <isSummary value="false"/>
      <binding>
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="chromosome-human"/>
        </extension>
        <strength value="example"/>
        <description value="Chromosome number for human"/>
        <valueSetReference>
          <reference value="http://hl7.org/fhir/ValueSet/chromosome-human"/>
        </valueSetReference>
      </binding>
    </element>
    <element id="Sequence.referenceSeq.genomeBuild">
      <path value="Sequence.referenceSeq.genomeBuild"/>
      <short value="The Genome Build used for reference, following GRCh build versions e.g. &apos;GRCh 37&apos;"/>
      <definition value="The Genome Build used for reference, following GRCh build versions e.g. &apos;GRCh 37&apos;. Version number must be included if a versioned release of a primary build was used."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="string"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.referenceSeq.referenceSeqId">
      <path value="Sequence.referenceSeq.referenceSeqId"/>
      <short value="Reference identifier"/>
      <definition value="Reference identifier of reference sequence submitted to NCBI. It must match the type in the Sequence.type field. For example, the prefix, &#8220;NG_&#8221; identifies reference sequence for genes, &#8220;NM_&#8221; for messenger RNA transcripts, and &#8220;NP_&#8221; for amino acid sequences."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="CodeableConcept"/>
      </type>
      <isSummary value="false"/>
      <binding>
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="sequenceReference"/>
        </extension>
        <strength value="example"/>
        <description value="Reference identifier"/>
        <valueSetReference>
          <reference value="http://hl7.org/fhir/ValueSet/sequence-referenceSeq"/>
        </valueSetReference>
      </binding>
    </element>
    <element id="Sequence.referenceSeq.referenceSeqPointer">
      <path value="Sequence.referenceSeq.referenceSeqPointer"/>
      <short value="A Pointer to another Sequence entity as reference sequence"/>
      <definition value="A Pointer to another Sequence entity as reference sequence."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="Reference"/>
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Sequence"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.referenceSeq.referenceSeqString">
      <path value="Sequence.referenceSeq.referenceSeqString"/>
      <short value="A string to represent reference sequence"/>
      <definition value="A string like &quot;ACGT&quot;."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="string"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.referenceSeq.strand">
      <path value="Sequence.referenceSeq.strand"/>
      <short value="Directionality of DNA ( +1/-1)"/>
      <definition value="Directionality of DNA sequence. Available values are &quot;1&quot; for the plus strand (5&apos; to 3&apos;)/Watson/Sense/positive and &quot;-1&quot; for the minus strand(3&apos; to 5&apos;)/Crick/Antisense/negative."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="integer"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.referenceSeq.windowStart">
      <path value="Sequence.referenceSeq.windowStart"/>
      <short value="Start position of the window on the reference sequence"/>
      <definition value="Start position of the window on the reference sequence. If the coordinate system is either 0-based or 1-based, then start position is inclusive."/>
      <min value="1"/>
      <max value="1"/>
      <type>
        <code value="integer"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.referenceSeq.windowEnd">
      <path value="Sequence.referenceSeq.windowEnd"/>
      <short value="End position of the window on the reference sequence"/>
      <definition value="End position of the window on the reference sequence. If the coordinate system is 0-based then end is is exclusive and does not include the last position. If the coordinate system is 1-base, then end is inclusive and includes the last position."/>
      <min value="1"/>
      <max value="1"/>
      <type>
        <code value="integer"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.variant">
      <path value="Sequence.variant"/>
      <short value="Variant in sequence"/>
      <definition value="The definition of variant here originates from Sequence ontology ([variant_of](http://www.sequenceontology.org/browser/current_svn/term/variant_of)). This element can represent amino acid or nucleic sequence change(including insertion,deletion,SNP,etc.) It can represent some complex mutation or segment variation with the assist of CIGAR string."/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="BackboneElement"/>
      </type>
      <constraint>
        <key value="ele-1"/>
        <severity value="error"/>
        <human value="All FHIR elements must have a @value or children"/>
        <expression value="hasValue() | (children().count() &gt; id.count())"/>
        <xpath value="@value|f:*|h:div"/>
        <source value="Element"/>
      </constraint>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.variant.id">
      <path value="Sequence.variant.id"/>
      <representation value="xmlAttr"/>
      <short value="xml:id (or equivalent in JSON)"/>
      <definition value="unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces."/>
      <min value="0"/>
      <max value="1"/>
      <base>
        <path value="Element.id"/>
        <min value="0"/>
        <max value="1"/>
      </base>
      <type>
        <code value="string"/>
      </type>
      <mapping>
        <identity value="rim"/>
        <map value="n/a"/>
      </mapping>
    </element>
    <element id="Sequence.variant.extension">
      <path value="Sequence.variant.extension"/>
      <short value="Additional Content defined by implementations"/>
      <definition value="May be used to represent additional information that is not part of the basic definition of the element. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension."/>
      <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone."/>
      <alias value="extensions"/>
      <alias value="user content"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Element.extension"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="Extension"/>
      </type>
      <mapping>
        <identity value="rim"/>
        <map value="n/a"/>
      </mapping>
    </element>
    <element id="Sequence.variant.modifierExtension">
      <path value="Sequence.variant.modifierExtension"/>
      <short value="Extensions that cannot be ignored"/>
      <definition value="May be used to represent additional information that is not part of the basic definition of the element, and that modifies the understanding of the element that contains it. Usually modifier elements provide negation or qualification. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions."/>
      <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone."/>
      <alias value="extensions"/>
      <alias value="user content"/>
      <alias value="modifiers"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="BackboneElement.modifierExtension"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="Extension"/>
      </type>
      <isModifier value="false"/>
      <isSummary value="false"/>
      <mapping>
        <identity value="rim"/>
        <map value="N/A"/>
      </mapping>
    </element>
    <element id="Sequence.variant.start">
      <path value="Sequence.variant.start"/>
      <short value="Start position of the variant on the reference sequence"/>
      <definition value="Start position of the variant on the reference sequence.If the coordinate system is either 0-based or 1-based, then start position is inclusive."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="integer"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.variant.end">
      <path value="Sequence.variant.end"/>
      <short value="End position of the variant on the reference sequence"/>
      <definition value="End position of the variant on the reference sequence.If the coordinate system is 0-based then end is is exclusive and does not include the last position. If the coordinate system is 1-base, then end is inclusive and includes the last position."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="integer"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.variant.observedAllele">
      <path value="Sequence.variant.observedAllele"/>
      <short value="Allele that was observed"/>
      <definition value="An allele is one of a set of coexisting sequence variants of a gene ([SO:0001023](http://www.sequenceontology.org/browser/current_svn/term/SO:0001023)). Nucleotide(s)/amino acids from start position of sequence to stop position of sequence on the positive (+) strand of the observed sequence. When the sequence type is DNA, it should be the sequence on the positive (+) strand. This will lay in the range between variant.start and variant.end."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="string"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.variant.referenceAllele">
      <path value="Sequence.variant.referenceAllele"/>
      <short value="Allele in the reference sequence"/>
      <definition value="An allele is one of a set of coexisting sequence variants of a gene ([SO:0001023](http://www.sequenceontology.org/browser/current_svn/term/SO:0001023)). Nucleotide(s)/amino acids from start position of sequence to stop position of sequence on the positive (+) strand of the reference sequence. When the sequence type is DNA, it should be the sequence on the positive (+) strand. This will lay in the range between variant.start and variant.end."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="string"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.variant.cigar">
      <path value="Sequence.variant.cigar"/>
      <short value="Extended CIGAR string for aligning the sequence with reference bases"/>
      <definition value="Extended CIGAR string for aligning the sequence with reference bases. See detailed documentation [here](http://support.illumina.com/help/SequencingAnalysisWorkflow/Content/Vault/Informatics/Sequencing_Analysis/CASAVA/swSEQ_mCA_ExtendedCIGARFormat.htm)."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="string"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.variant.variantPointer">
      <path value="Sequence.variant.variantPointer"/>
      <short value="Pointer to observed variant information"/>
      <definition value="A pointer to an Observation containing variant information."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="Reference"/>
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Observation"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.observedSeq">
      <path value="Sequence.observedSeq"/>
      <short value="Sequence that was observed"/>
      <definition value="Sequence that was observed. It is the result marked by referenceSeq along with variant records on referenceSeq. This shall starts from referenceSeq.windowStart and end by referenceSeq.windowEnd."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="string"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quality">
      <path value="Sequence.quality"/>
      <short value="An set of value as quality of sequence"/>
      <definition value="An experimental feature attribute that defines the quality of the feature in a quantitative way, such as a phred quality score ([SO:0001686](http://www.sequenceontology.org/browser/current_svn/term/SO:0001686))."/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="BackboneElement"/>
      </type>
      <constraint>
        <key value="ele-1"/>
        <severity value="error"/>
        <human value="All FHIR elements must have a @value or children"/>
        <expression value="hasValue() | (children().count() &gt; id.count())"/>
        <xpath value="@value|f:*|h:div"/>
        <source value="Element"/>
      </constraint>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quality.id">
      <path value="Sequence.quality.id"/>
      <representation value="xmlAttr"/>
      <short value="xml:id (or equivalent in JSON)"/>
      <definition value="unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces."/>
      <min value="0"/>
      <max value="1"/>
      <base>
        <path value="Element.id"/>
        <min value="0"/>
        <max value="1"/>
      </base>
      <type>
        <code value="string"/>
      </type>
      <mapping>
        <identity value="rim"/>
        <map value="n/a"/>
      </mapping>
    </element>
    <element id="Sequence.quality.extension">
      <path value="Sequence.quality.extension"/>
      <short value="Additional Content defined by implementations"/>
      <definition value="May be used to represent additional information that is not part of the basic definition of the element. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension."/>
      <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone."/>
      <alias value="extensions"/>
      <alias value="user content"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Element.extension"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="Extension"/>
      </type>
      <mapping>
        <identity value="rim"/>
        <map value="n/a"/>
      </mapping>
    </element>
    <element id="Sequence.quality.modifierExtension">
      <path value="Sequence.quality.modifierExtension"/>
      <short value="Extensions that cannot be ignored"/>
      <definition value="May be used to represent additional information that is not part of the basic definition of the element, and that modifies the understanding of the element that contains it. Usually modifier elements provide negation or qualification. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions."/>
      <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone."/>
      <alias value="extensions"/>
      <alias value="user content"/>
      <alias value="modifiers"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="BackboneElement.modifierExtension"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="Extension"/>
      </type>
      <isModifier value="false"/>
      <isSummary value="false"/>
      <mapping>
        <identity value="rim"/>
        <map value="N/A"/>
      </mapping>
    </element>
    <element id="Sequence.quality.type">
      <path value="Sequence.quality.type"/>
      <short value="indel | snp | unknown"/>
      <definition value="INDEL / SNP / Undefined variant."/>
      <min value="1"/>
      <max value="1"/>
      <type>
        <code value="code"/>
      </type>
      <isSummary value="false"/>
      <binding>
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="qualityType"/>
        </extension>
        <strength value="required"/>
        <description value="Type for quality report"/>
        <valueSetReference>
          <reference value="http://hl7.org/fhir/ValueSet/quality-type"/>
        </valueSetReference>
      </binding>
    </element>
    <element id="Sequence.quality.standardSequence">
      <path value="Sequence.quality.standardSequence"/>
      <short value="Standard sequence for comparison"/>
      <definition value="Gold standard sequence used for comparing against."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="CodeableConcept"/>
      </type>
      <isSummary value="false"/>
      <binding>
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="qualityStandardSequence"/>
        </extension>
        <strength value="example"/>
        <description value="Reference identifier of the sequence that used to mark the quality of tested samples."/>
        <valueSetReference>
          <reference value="http://hl7.org/fhir/ValueSet/sequence-quality-standardSequence"/>
        </valueSetReference>
      </binding>
    </element>
    <element id="Sequence.quality.start">
      <path value="Sequence.quality.start"/>
      <short value="Start position of the sequence"/>
      <definition value="Start position of the sequence. If the coordinate system is either 0-based or 1-based, then start position is inclusive."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="integer"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quality.end">
      <path value="Sequence.quality.end"/>
      <short value="End position of the sequence"/>
      <definition value="End position of the sequence.If the coordinate system is 0-based then end is is exclusive and does not include the last position. If the coordinate system is 1-base, then end is inclusive and includes the last position."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="integer"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quality.score">
      <path value="Sequence.quality.score"/>
      <short value="Quality score for the comparison"/>
      <definition value="The score of an experimentally derived feature such as a p-value ([SO:0001685](http://www.sequenceontology.org/browser/current_svn/term/SO:0001685))."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="Quantity"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quality.method">
      <path value="Sequence.quality.method"/>
      <short value="Method to get quality"/>
      <definition value="Which method is used to get sequence quality."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="CodeableConcept"/>
      </type>
      <isSummary value="false"/>
      <binding>
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="qualityMethod"/>
        </extension>
        <strength value="example"/>
        <description value="The method used to evaluate the numerical quality of the observed sequence."/>
        <valueSetReference>
          <reference value="http://hl7.org/fhir/ValueSet/sequence-quality-method"/>
        </valueSetReference>
      </binding>
    </element>
    <element id="Sequence.quality.truthTP">
      <path value="Sequence.quality.truthTP"/>
      <short value="True positives from the perspective of the truth data"/>
      <definition value="True positives, from the perspective of the truth data, i.e. the number of sites in the Truth Call Set for which there are paths through the Query Call Set that are consistent with all of the alleles at this site, and for which there is an accurate genotype call for the event."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="decimal"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quality.queryTP">
      <path value="Sequence.quality.queryTP"/>
      <short value="True positives from the perspective of the query data"/>
      <definition value="True positives, from the perspective of the query data, i.e. the number of sites in the Query Call Set for which there are paths through the Truth Call Set that are consistent with all of the alleles at this site, and for which there is an accurate genotype call for the event."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="decimal"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quality.truthFN">
      <path value="Sequence.quality.truthFN"/>
      <short value="False negatives"/>
      <definition value="False negatives, i.e. the number of sites in the Truth Call Set for which there is no path through the Query Call Set that is consistent with all of the alleles at this site, or sites for which there is an inaccurate genotype call for the event. Sites with correct variant but incorrect genotype are counted here."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="decimal"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quality.queryFP">
      <path value="Sequence.quality.queryFP"/>
      <short value="False positives"/>
      <definition value="False positives, i.e. the number of sites in the Query Call Set for which there is no path through the Truth Call Set that is consistent with this site. Sites with correct variant but incorrect genotype are counted here."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="decimal"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quality.gtFP">
      <path value="Sequence.quality.gtFP"/>
      <short value="False positives where the non-REF alleles in the Truth and Query Call Sets match"/>
      <definition value="The number of false positives where the non-REF alleles in the Truth and Query Call Sets match (i.e. cases where the truth is 1/1 and the query is 0/1 or similar)."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="decimal"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quality.precision">
      <path value="Sequence.quality.precision"/>
      <short value="Precision of comparison"/>
      <definition value="QUERY.TP / (QUERY.TP + QUERY.FP)."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="decimal"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quality.recall">
      <path value="Sequence.quality.recall"/>
      <short value="Recall of comparison"/>
      <definition value="TRUTH.TP / (TRUTH.TP + TRUTH.FN)."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="decimal"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quality.fScore">
      <path value="Sequence.quality.fScore"/>
      <short value="F-score"/>
      <definition value="Harmonic mean of Recall and Precision, computed as: 2 * precision * recall / (precision + recall)."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="decimal"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.readCoverage">
      <path value="Sequence.readCoverage"/>
      <short value="Average number of reads representing a given nucleotide in the reconstructed sequence"/>
      <definition value="Coverage (read depth or depth) is the average number of reads representing a given nucleotide in the reconstructed sequence."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="integer"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.repository">
      <path value="Sequence.repository"/>
      <short value="External repository which contains detailed report related with observedSeq in this resource"/>
      <definition value="Configurations of the external repository. The repository shall store target&apos;s observedSeq or records related with target&apos;s observedSeq."/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="BackboneElement"/>
      </type>
      <constraint>
        <key value="ele-1"/>
        <severity value="error"/>
        <human value="All FHIR elements must have a @value or children"/>
        <expression value="hasValue() | (children().count() &gt; id.count())"/>
        <xpath value="@value|f:*|h:div"/>
        <source value="Element"/>
      </constraint>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.repository.id">
      <path value="Sequence.repository.id"/>
      <representation value="xmlAttr"/>
      <short value="xml:id (or equivalent in JSON)"/>
      <definition value="unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces."/>
      <min value="0"/>
      <max value="1"/>
      <base>
        <path value="Element.id"/>
        <min value="0"/>
        <max value="1"/>
      </base>
      <type>
        <code value="string"/>
      </type>
      <mapping>
        <identity value="rim"/>
        <map value="n/a"/>
      </mapping>
    </element>
    <element id="Sequence.repository.extension">
      <path value="Sequence.repository.extension"/>
      <short value="Additional Content defined by implementations"/>
      <definition value="May be used to represent additional information that is not part of the basic definition of the element. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension."/>
      <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone."/>
      <alias value="extensions"/>
      <alias value="user content"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="Element.extension"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="Extension"/>
      </type>
      <mapping>
        <identity value="rim"/>
        <map value="n/a"/>
      </mapping>
    </element>
    <element id="Sequence.repository.modifierExtension">
      <path value="Sequence.repository.modifierExtension"/>
      <short value="Extensions that cannot be ignored"/>
      <definition value="May be used to represent additional information that is not part of the basic definition of the element, and that modifies the understanding of the element that contains it. Usually modifier elements provide negation or qualification. In order to make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer is allowed to define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions."/>
      <comment value="There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone."/>
      <alias value="extensions"/>
      <alias value="user content"/>
      <alias value="modifiers"/>
      <min value="0"/>
      <max value="*"/>
      <base>
        <path value="BackboneElement.modifierExtension"/>
        <min value="0"/>
        <max value="*"/>
      </base>
      <type>
        <code value="Extension"/>
      </type>
      <isModifier value="false"/>
      <isSummary value="false"/>
      <mapping>
        <identity value="rim"/>
        <map value="N/A"/>
      </mapping>
    </element>
    <element id="Sequence.repository.type">
      <path value="Sequence.repository.type"/>
      <short value="directlink | openapi | login | oauth | other"/>
      <definition value="Click and see / RESTful API / Need login to see / RESTful API with authentication / Other ways to see resource."/>
      <min value="1"/>
      <max value="1"/>
      <type>
        <code value="code"/>
      </type>
      <isSummary value="false"/>
      <binding>
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="repositoryType"/>
        </extension>
        <strength value="required"/>
        <description value="Type for access of external URI"/>
        <valueSetReference>
          <reference value="http://hl7.org/fhir/ValueSet/repository-type"/>
        </valueSetReference>
      </binding>
    </element>
    <element id="Sequence.repository.url">
      <path value="Sequence.repository.url"/>
      <short value="URI of the repository"/>
      <definition value="URI of an external repository which contains further details about the genetics data."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="uri"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.repository.name">
      <path value="Sequence.repository.name"/>
      <short value="Repository&apos;s name"/>
      <definition value="URI of an external repository which contains further details about the genetics data."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="string"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.repository.datasetId">
      <path value="Sequence.repository.datasetId"/>
      <short value="Id of the dataset that used to call for dataset in repository"/>
      <definition value="Id of the variant in this external repository. The server will understand how to use this id to call for more info about datasets in external repository."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="string"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.repository.variantsetId">
      <path value="Sequence.repository.variantsetId"/>
      <short value="Id of the variantset that used to call for variantset in repository"/>
      <definition value="Id of the variantset in this external repository. The server will understand how to use this id to call for more info about variantsets in external repository."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="string"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.repository.readsetId">
      <path value="Sequence.repository.readsetId"/>
      <short value="Id of the read"/>
      <definition value="Id of the read in this external repository."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="string"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.pointer">
      <path value="Sequence.pointer"/>
      <short value="Pointer to next atomic sequence"/>
      <definition value="Pointer to next atomic sequence which at most contains one variant."/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="Reference"/>
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Sequence"/>
      </type>
      <isSummary value="false"/>
    </element>
  </snapshot>
  <differential>
    <element id="Sequence">
      <path value="Sequence"/>
      <short value="Information about a biological sequence"/>
      <definition value="Raw data describing a biological sequence."/>
      <min value="0"/>
      <max value="*"/>
      <constraint>
        <key value="seq-3"/>
        <severity value="error"/>
        <human value="Only 0 and 1 are valid for coordinateSystem"/>
        <expression value="coordinateSystem = 1 or coordinateSystem = 0"/>
        <xpath value="count(f:coordinateSystem[@value=0 and @value=1]) = 1"/>
      </constraint>
      <mapping>
        <identity value="w5"/>
        <map value="clinical.diagnostics"/>
      </mapping>
    </element>
    <element id="Sequence.identifier">
      <path value="Sequence.identifier"/>
      <short value="Unique ID for this particular sequence. This is a FHIR-defined id"/>
      <definition value="A unique identifier for this particular sequence instance. This is a FHIR-defined id."/>
      <requirements value="Allows sequences to be distinguished and referenced."/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="Identifier"/>
      </type>
      <isSummary value="false"/>
      <mapping>
        <identity value="w5"/>
        <map value="id"/>
      </mapping>
    </element>
    <element id="Sequence.type">
      <path value="Sequence.type"/>
      <short value="aa | dna | rna"/>
      <definition value="Amino Acid Sequence/ DNA Sequence / RNA Sequence."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="code"/>
      </type>
      <isSummary value="false"/>
      <binding>
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="sequenceType"/>
        </extension>
        <strength value="example"/>
        <description value="Type if a sequence -- DNA, RNA, or amino acid sequence"/>
        <valueSetReference>
          <reference value="http://hl7.org/fhir/ValueSet/sequence-type"/>
        </valueSetReference>
      </binding>
    </element>
    <element id="Sequence.coordinateSystem">
      <path value="Sequence.coordinateSystem"/>
      <short value="Base number of coordinate system (0 for 0-based numbering or coordinates, inclusive start, exclusive end, 1 for 1-based numbering, inclusive start, inclusive end)"/>
      <definition value="Whether the sequence is numbered starting at 0 (0-based numbering or coordinates, inclusive start, exclusive end) or starting at 1 (1-based numbering, inclusive start and inclusive end)."/>
      <min value="1"/>
      <max value="1"/>
      <type>
        <code value="integer"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.patient">
      <path value="Sequence.patient"/>
      <short value="Who and/or what this is about"/>
      <definition value="The patient whose sequencing results are described by this resource."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="Reference"/>
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Patient"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.specimen">
      <path value="Sequence.specimen"/>
      <short value="Specimen used for sequencing"/>
      <definition value="Specimen used for sequencing."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="Reference"/>
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Specimen"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.device">
      <path value="Sequence.device"/>
      <short value="The method for sequencing"/>
      <definition value="The method for sequencing, for example, chip information."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="Reference"/>
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Device"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.performer">
      <path value="Sequence.performer"/>
      <short value="Who should be responsible for test result"/>
      <definition value="The organization or lab that should be responsible for this result."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="Reference"/>
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Organization"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quantity">
      <path value="Sequence.quantity"/>
      <short value="The number of copies of the seqeunce of interest. (RNASeq)"/>
      <definition value="The number of copies of the seqeunce of interest. (RNASeq)."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="Quantity"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.referenceSeq">
      <path value="Sequence.referenceSeq"/>
      <short value="A sequence used as reference"/>
      <definition value="A sequence that is used as a reference to describe variants that are present in a sequence analyzed."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="BackboneElement"/>
      </type>
      <constraint>
        <key value="seq-4"/>
        <severity value="error"/>
        <human value="Only +1 and -1 are valid for strand"/>
        <expression value="strand.empty() or strand = 1 or strand = -1"/>
        <xpath value="not(exists(f:strand)) or count(f:strand[@value=-1 and @value=1]) = 1"/>
      </constraint>
      <constraint>
        <key value="seq-5"/>
        <severity value="error"/>
        <human value="GenomeBuild and chromosome must be both contained if either one of them is contained"/>
        <expression value="(chromosome.empty() and genomeBuild.empty()) or (chromosome.exists() and genomeBuild.exists())"/>
        <xpath value="(exists(f:chromosome) and exists(f:genomeBuild)) or (not(exists(f:chromosome)) and not(exists(f:genomeBuild)))"/>
      </constraint>
      <constraint>
        <key value="seq-6"/>
        <severity value="error"/>
        <human value="Have and only have one of the following elements in referenceSeq : 1. genomeBuild 2 referenceSeqId 3. referenceSeqPointer 4. referenceSeqString"/>
        <expression value="(genomeBuild.count()+referenceSeqId.count()+ referenceSeqPointer.count()+ referenceSeqString.count()) = 1"/>
        <xpath value="count(f:genomeBuild)+count(f:referenceSeqId)+count(f:referenceSeqPointer)+count(f:referenceSeqString)=1"/>
      </constraint>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.referenceSeq.chromosome">
      <path value="Sequence.referenceSeq.chromosome"/>
      <short value="Chromosome containing genetic finding"/>
      <definition value="Structural unit composed of a nucleic acid molecule which controls its own replication through the interaction of specific proteins at one or more origins of replication ([SO:0000340](http://www.sequenceontology.org/browser/current_svn/term/SO:0000340))."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="CodeableConcept"/>
      </type>
      <isSummary value="false"/>
      <binding>
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="chromosome-human"/>
        </extension>
        <strength value="example"/>
        <description value="Chromosome number for human"/>
        <valueSetReference>
          <reference value="http://hl7.org/fhir/ValueSet/chromosome-human"/>
        </valueSetReference>
      </binding>
    </element>
    <element id="Sequence.referenceSeq.genomeBuild">
      <path value="Sequence.referenceSeq.genomeBuild"/>
      <short value="The Genome Build used for reference, following GRCh build versions e.g. &apos;GRCh 37&apos;"/>
      <definition value="The Genome Build used for reference, following GRCh build versions e.g. &apos;GRCh 37&apos;. Version number must be included if a versioned release of a primary build was used."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="string"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.referenceSeq.referenceSeqId">
      <path value="Sequence.referenceSeq.referenceSeqId"/>
      <short value="Reference identifier"/>
      <definition value="Reference identifier of reference sequence submitted to NCBI. It must match the type in the Sequence.type field. For example, the prefix, &#8220;NG_&#8221; identifies reference sequence for genes, &#8220;NM_&#8221; for messenger RNA transcripts, and &#8220;NP_&#8221; for amino acid sequences."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="CodeableConcept"/>
      </type>
      <isSummary value="false"/>
      <binding>
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="sequenceReference"/>
        </extension>
        <strength value="example"/>
        <description value="Reference identifier"/>
        <valueSetReference>
          <reference value="http://hl7.org/fhir/ValueSet/sequence-referenceSeq"/>
        </valueSetReference>
      </binding>
    </element>
    <element id="Sequence.referenceSeq.referenceSeqPointer">
      <path value="Sequence.referenceSeq.referenceSeqPointer"/>
      <short value="A Pointer to another Sequence entity as reference sequence"/>
      <definition value="A Pointer to another Sequence entity as reference sequence."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="Reference"/>
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Sequence"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.referenceSeq.referenceSeqString">
      <path value="Sequence.referenceSeq.referenceSeqString"/>
      <short value="A string to represent reference sequence"/>
      <definition value="A string like &quot;ACGT&quot;."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="string"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.referenceSeq.strand">
      <path value="Sequence.referenceSeq.strand"/>
      <short value="Directionality of DNA ( +1/-1)"/>
      <definition value="Directionality of DNA sequence. Available values are &quot;1&quot; for the plus strand (5&apos; to 3&apos;)/Watson/Sense/positive and &quot;-1&quot; for the minus strand(3&apos; to 5&apos;)/Crick/Antisense/negative."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="integer"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.referenceSeq.windowStart">
      <path value="Sequence.referenceSeq.windowStart"/>
      <short value="Start position of the window on the reference sequence"/>
      <definition value="Start position of the window on the reference sequence. If the coordinate system is either 0-based or 1-based, then start position is inclusive."/>
      <min value="1"/>
      <max value="1"/>
      <type>
        <code value="integer"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.referenceSeq.windowEnd">
      <path value="Sequence.referenceSeq.windowEnd"/>
      <short value="End position of the window on the reference sequence"/>
      <definition value="End position of the window on the reference sequence. If the coordinate system is 0-based then end is is exclusive and does not include the last position. If the coordinate system is 1-base, then end is inclusive and includes the last position."/>
      <min value="1"/>
      <max value="1"/>
      <type>
        <code value="integer"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.variant">
      <path value="Sequence.variant"/>
      <short value="Variant in sequence"/>
      <definition value="The definition of variant here originates from Sequence ontology ([variant_of](http://www.sequenceontology.org/browser/current_svn/term/variant_of)). This element can represent amino acid or nucleic sequence change(including insertion,deletion,SNP,etc.) It can represent some complex mutation or segment variation with the assist of CIGAR string."/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="BackboneElement"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.variant.start">
      <path value="Sequence.variant.start"/>
      <short value="Start position of the variant on the reference sequence"/>
      <definition value="Start position of the variant on the reference sequence.If the coordinate system is either 0-based or 1-based, then start position is inclusive."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="integer"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.variant.end">
      <path value="Sequence.variant.end"/>
      <short value="End position of the variant on the reference sequence"/>
      <definition value="End position of the variant on the reference sequence.If the coordinate system is 0-based then end is is exclusive and does not include the last position. If the coordinate system is 1-base, then end is inclusive and includes the last position."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="integer"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.variant.observedAllele">
      <path value="Sequence.variant.observedAllele"/>
      <short value="Allele that was observed"/>
      <definition value="An allele is one of a set of coexisting sequence variants of a gene ([SO:0001023](http://www.sequenceontology.org/browser/current_svn/term/SO:0001023)). Nucleotide(s)/amino acids from start position of sequence to stop position of sequence on the positive (+) strand of the observed sequence. When the sequence type is DNA, it should be the sequence on the positive (+) strand. This will lay in the range between variant.start and variant.end."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="string"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.variant.referenceAllele">
      <path value="Sequence.variant.referenceAllele"/>
      <short value="Allele in the reference sequence"/>
      <definition value="An allele is one of a set of coexisting sequence variants of a gene ([SO:0001023](http://www.sequenceontology.org/browser/current_svn/term/SO:0001023)). Nucleotide(s)/amino acids from start position of sequence to stop position of sequence on the positive (+) strand of the reference sequence. When the sequence type is DNA, it should be the sequence on the positive (+) strand. This will lay in the range between variant.start and variant.end."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="string"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.variant.cigar">
      <path value="Sequence.variant.cigar"/>
      <short value="Extended CIGAR string for aligning the sequence with reference bases"/>
      <definition value="Extended CIGAR string for aligning the sequence with reference bases. See detailed documentation [here](http://support.illumina.com/help/SequencingAnalysisWorkflow/Content/Vault/Informatics/Sequencing_Analysis/CASAVA/swSEQ_mCA_ExtendedCIGARFormat.htm)."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="string"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.variant.variantPointer">
      <path value="Sequence.variant.variantPointer"/>
      <short value="Pointer to observed variant information"/>
      <definition value="A pointer to an Observation containing variant information."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="Reference"/>
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Observation"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.observedSeq">
      <path value="Sequence.observedSeq"/>
      <short value="Sequence that was observed"/>
      <definition value="Sequence that was observed. It is the result marked by referenceSeq along with variant records on referenceSeq. This shall starts from referenceSeq.windowStart and end by referenceSeq.windowEnd."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="string"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quality">
      <path value="Sequence.quality"/>
      <short value="An set of value as quality of sequence"/>
      <definition value="An experimental feature attribute that defines the quality of the feature in a quantitative way, such as a phred quality score ([SO:0001686](http://www.sequenceontology.org/browser/current_svn/term/SO:0001686))."/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="BackboneElement"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quality.type">
      <path value="Sequence.quality.type"/>
      <short value="indel | snp | unknown"/>
      <definition value="INDEL / SNP / Undefined variant."/>
      <min value="1"/>
      <max value="1"/>
      <type>
        <code value="code"/>
      </type>
      <isSummary value="false"/>
      <binding>
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="qualityType"/>
        </extension>
        <strength value="required"/>
        <description value="Type for quality report"/>
        <valueSetReference>
          <reference value="http://hl7.org/fhir/ValueSet/quality-type"/>
        </valueSetReference>
      </binding>
    </element>
    <element id="Sequence.quality.standardSequence">
      <path value="Sequence.quality.standardSequence"/>
      <short value="Standard sequence for comparison"/>
      <definition value="Gold standard sequence used for comparing against."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="CodeableConcept"/>
      </type>
      <isSummary value="false"/>
      <binding>
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="qualityStandardSequence"/>
        </extension>
        <strength value="example"/>
        <description value="Reference identifier of the sequence that used to mark the quality of tested samples."/>
        <valueSetReference>
          <reference value="http://hl7.org/fhir/ValueSet/sequence-quality-standardSequence"/>
        </valueSetReference>
      </binding>
    </element>
    <element id="Sequence.quality.start">
      <path value="Sequence.quality.start"/>
      <short value="Start position of the sequence"/>
      <definition value="Start position of the sequence. If the coordinate system is either 0-based or 1-based, then start position is inclusive."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="integer"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quality.end">
      <path value="Sequence.quality.end"/>
      <short value="End position of the sequence"/>
      <definition value="End position of the sequence.If the coordinate system is 0-based then end is is exclusive and does not include the last position. If the coordinate system is 1-base, then end is inclusive and includes the last position."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="integer"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quality.score">
      <path value="Sequence.quality.score"/>
      <short value="Quality score for the comparison"/>
      <definition value="The score of an experimentally derived feature such as a p-value ([SO:0001685](http://www.sequenceontology.org/browser/current_svn/term/SO:0001685))."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="Quantity"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quality.method">
      <path value="Sequence.quality.method"/>
      <short value="Method to get quality"/>
      <definition value="Which method is used to get sequence quality."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="CodeableConcept"/>
      </type>
      <isSummary value="false"/>
      <binding>
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="qualityMethod"/>
        </extension>
        <strength value="example"/>
        <description value="The method used to evaluate the numerical quality of the observed sequence."/>
        <valueSetReference>
          <reference value="http://hl7.org/fhir/ValueSet/sequence-quality-method"/>
        </valueSetReference>
      </binding>
    </element>
    <element id="Sequence.quality.truthTP">
      <path value="Sequence.quality.truthTP"/>
      <short value="True positives from the perspective of the truth data"/>
      <definition value="True positives, from the perspective of the truth data, i.e. the number of sites in the Truth Call Set for which there are paths through the Query Call Set that are consistent with all of the alleles at this site, and for which there is an accurate genotype call for the event."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="decimal"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quality.queryTP">
      <path value="Sequence.quality.queryTP"/>
      <short value="True positives from the perspective of the query data"/>
      <definition value="True positives, from the perspective of the query data, i.e. the number of sites in the Query Call Set for which there are paths through the Truth Call Set that are consistent with all of the alleles at this site, and for which there is an accurate genotype call for the event."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="decimal"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quality.truthFN">
      <path value="Sequence.quality.truthFN"/>
      <short value="False negatives"/>
      <definition value="False negatives, i.e. the number of sites in the Truth Call Set for which there is no path through the Query Call Set that is consistent with all of the alleles at this site, or sites for which there is an inaccurate genotype call for the event. Sites with correct variant but incorrect genotype are counted here."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="decimal"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quality.queryFP">
      <path value="Sequence.quality.queryFP"/>
      <short value="False positives"/>
      <definition value="False positives, i.e. the number of sites in the Query Call Set for which there is no path through the Truth Call Set that is consistent with this site. Sites with correct variant but incorrect genotype are counted here."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="decimal"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quality.gtFP">
      <path value="Sequence.quality.gtFP"/>
      <short value="False positives where the non-REF alleles in the Truth and Query Call Sets match"/>
      <definition value="The number of false positives where the non-REF alleles in the Truth and Query Call Sets match (i.e. cases where the truth is 1/1 and the query is 0/1 or similar)."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="decimal"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quality.precision">
      <path value="Sequence.quality.precision"/>
      <short value="Precision of comparison"/>
      <definition value="QUERY.TP / (QUERY.TP + QUERY.FP)."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="decimal"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quality.recall">
      <path value="Sequence.quality.recall"/>
      <short value="Recall of comparison"/>
      <definition value="TRUTH.TP / (TRUTH.TP + TRUTH.FN)."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="decimal"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.quality.fScore">
      <path value="Sequence.quality.fScore"/>
      <short value="F-score"/>
      <definition value="Harmonic mean of Recall and Precision, computed as: 2 * precision * recall / (precision + recall)."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="decimal"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.readCoverage">
      <path value="Sequence.readCoverage"/>
      <short value="Average number of reads representing a given nucleotide in the reconstructed sequence"/>
      <definition value="Coverage (read depth or depth) is the average number of reads representing a given nucleotide in the reconstructed sequence."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="integer"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.repository">
      <path value="Sequence.repository"/>
      <short value="External repository which contains detailed report related with observedSeq in this resource"/>
      <definition value="Configurations of the external repository. The repository shall store target&apos;s observedSeq or records related with target&apos;s observedSeq."/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="BackboneElement"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.repository.type">
      <path value="Sequence.repository.type"/>
      <short value="directlink | openapi | login | oauth | other"/>
      <definition value="Click and see / RESTful API / Need login to see / RESTful API with authentication / Other ways to see resource."/>
      <min value="1"/>
      <max value="1"/>
      <type>
        <code value="code"/>
      </type>
      <isSummary value="false"/>
      <binding>
        <extension url="http://hl7.org/fhir/StructureDefinition/elementdefinition-bindingName">
          <valueString value="repositoryType"/>
        </extension>
        <strength value="required"/>
        <description value="Type for access of external URI"/>
        <valueSetReference>
          <reference value="http://hl7.org/fhir/ValueSet/repository-type"/>
        </valueSetReference>
      </binding>
    </element>
    <element id="Sequence.repository.url">
      <path value="Sequence.repository.url"/>
      <short value="URI of the repository"/>
      <definition value="URI of an external repository which contains further details about the genetics data."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="uri"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.repository.name">
      <path value="Sequence.repository.name"/>
      <short value="Repository&apos;s name"/>
      <definition value="URI of an external repository which contains further details about the genetics data."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="string"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.repository.datasetId">
      <path value="Sequence.repository.datasetId"/>
      <short value="Id of the dataset that used to call for dataset in repository"/>
      <definition value="Id of the variant in this external repository. The server will understand how to use this id to call for more info about datasets in external repository."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="string"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.repository.variantsetId">
      <path value="Sequence.repository.variantsetId"/>
      <short value="Id of the variantset that used to call for variantset in repository"/>
      <definition value="Id of the variantset in this external repository. The server will understand how to use this id to call for more info about variantsets in external repository."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="string"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.repository.readsetId">
      <path value="Sequence.repository.readsetId"/>
      <short value="Id of the read"/>
      <definition value="Id of the read in this external repository."/>
      <min value="0"/>
      <max value="1"/>
      <type>
        <code value="string"/>
      </type>
      <isSummary value="false"/>
    </element>
    <element id="Sequence.pointer">
      <path value="Sequence.pointer"/>
      <short value="Pointer to next atomic sequence"/>
      <definition value="Pointer to next atomic sequence which at most contains one variant."/>
      <min value="0"/>
      <max value="*"/>
      <type>
        <code value="Reference"/>
        <targetProfile value="http://hl7.org/fhir/StructureDefinition/Sequence"/>
      </type>
      <isSummary value="false"/>
    </element>
  </differential>
</StructureDefinition>